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Article

A novel oncolytic adenovirus selectively silences the expression of tumor-associated STAT3 and exhibits potent antitumoral activity.

Carcinogenesis - 1 Dec 2009

Han Zhiqiang, Hong Zhenya, Chen Caihong, Gao Qinglei, Luo Danfeng, Fang Yong, Cao Yang, Zhu Tao, Jiang Xuefeng, Ma Quanfu, Li Wei, Han Lingfei, Wang Daowen, Xu Gang, Wang Shixuan, Meng Li, Zhou Jianfeng, Ma Ding

Abstract excerpt

Tumor cells acquire the ability to proliferate uncontrollably, resist apoptosis, sustain angiogenesis and evade immune surveillance. Signal transducer and activator of transcription (STAT) 3 regulates all of these processes in a surprisingly large number of human cancers. Consequently, the STAT3...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19843641
DOI: 10.1093/carcin/bgp249

Genes

STAT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19843641-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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