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Senecavirus A as an Oncolytic Virus: Prospects, Challenges and Development Directions

17 Mar 2022

Abstract excerpt

Oncolytic viruses have the capacity to selectively kill infected tumor cells and trigger protective immunity. As such, oncolytic virotherapy has become a promising immunotherapy strategy against cancer. A variety of viruses from different families have been proven to have oncolytic potential. Senecavirus A (SVA) was the first picornavirus to be tested in humans for its oncolytic potential and was shown to...

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PMID: 35371972
DOI: 10.3389/fonc.2022.839536

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