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Adenovirus Biology, Recombinant Adenovirus, and Adenovirus Usage in Gene Therapy

14 Dec 2021

Abstract excerpt

Gene therapy is currently in the public spotlight. Several gene therapy products, including oncolytic virus (OV), which predominantly replicates in and kills cancer cells, and COVID-19 vaccines have recently been commercialized. Recombinant adenoviruses, including replication-defective adenoviral vector and conditionally replicating adenovirus (CRA; oncolytic adenovirus), have been extensively studied and used in...

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PMID: 34960772
DOI: 10.3390/v13122502

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