Article
Environmental enrichment reduces mechanical hypersensitivity in neuropathic mice, but fails to abolish the phenotype of CCK2 receptor deficient mice.
Neuroscience letters - 31 Dec 2009
Abramov Urho, Kurrikoff Kaido, Matsui Toshimitsu, Vasar Eero
Abstract excerpt
Genetic invalidation of CCK(2) receptors abolishes chronic constriction injury (CCI) induced mechanical hypersensitivity in mice. However, housing in environmentally enriched conditions significantly alters the phenotype of CCK(2) receptor deficient mice in all major behavioral domains. Furthermore, environmental enrichment itself has been reported to have protective effects in several rodent models of...
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