Deficit in voluntary wheel running in chronic inflammatory and neuropathic pain models in mice: Impact of sex and genotype.

doi:10.1016/j.bbr.2020.113009

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Article

Deficit in voluntary wheel running in chronic inflammatory and neuropathic pain models in mice: Impact of sex and genotype.

Behavioural brain research - 5 Feb 2021

Contreras Katherine M, Caillaud Martial, Neddenriep Bradley, Bagdas Deniz, Roberts Jane L, Ulker Esad, White Alyssa B, Aboulhosn Raneem, Toma Wisam, Khalefa Tala, Adel Ahd, Mann Jared A, Damaj M Imad

Abstract excerpt

Patients with chronic pain report decreased general activity and emotional distress. Therefore, the development of various animal models that encompass different aspects of pain are crucial for the discovery of genetic differences and the assessment of novel analgesics to improve quality of life. C57BL/6J and DBA/2J mice received unilateral intraplantar injections of 100 % CFA, paclitaxel, or CCI surgery to...

Topics

Adjuvants, Immunologic
Animals
Antineoplastic Agents, Phytogenic
Chronic Pain
Disease Models, Animal
Female
Freund's Adjuvant
Genotype
Hyperalgesia
Inflammation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Mice

Mice, Inbred C57BL

Mice, Inbred DBA

Motor Activity

Neuralgia

Nociceptive Pain

Paclitaxel

Source

Open in PubMed Open full text

Identifiers

PMID: 33181181
DOI: 10.1016/j.bbr.2020.113009
PMCID: PMC8961431

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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