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Article

Behavioral phenotypes of mice lacking purinergic P2X4 receptors in acute and chronic pain assays.

Molecular pain - 11 Jun 2009

Tsuda Makoto, Kuboyama Kazuya, Inoue Tomoyuki, Nagata Kenichiro, Tozaki-Saitoh Hidetoshi, Inoue Kazuhide

Abstract excerpt

A growing body of evidence indicates that P2X receptors (P2XRs), a family of ligand-gated cation channels activated by extracellular ATP, play an important role in pain signaling. In contrast to the role of the P2X3R subtype that has been extensively studied, the precise roles of others among the seven P2XR subtypes (P2X1R-P2X7R) remain to be determined because of a lack of sufficiently powerful tools to...

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Identifiers

PMID: 19515262
DOI: 10.1186/1744-8069-5-28
PMCID: PMC2704200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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