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Article

TNFα gene G-308A polymorphism and the risk of ischemic stroke.

Neurologia i neurochirurgia polska - 1 Jan 2014

Wawrzynek Alicja, Dobiała Jacek, Wender Mieczysław, Kozubski Wojciech, Michałowska-Wender Grażyna

Abstract excerpt

TNFα, a significant immune mediator, may contribute to the initiation and progression of the ischemic stroke. Genetics of TNFα molecule may have an important role in the risk of ischemic stroke. The most interesting aspects of the G-308A polymorphism remain unexplained; there are many discrepancies between the results. Differences in the ethnicity of the studied cohorts may be taken as one of the possibility. Our...

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PMID: 25482248
DOI: 10.1016/j.pjnns.2014.09.007

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