Article
Single nucleotide polymorphisms in promoter of angiotensin II type 1 receptor gene associated with essential hypertension and coronary heart disease in Chinese population.
Acta pharmacologica Sinica - 1 Nov 2003
Jin Wei, Liu Yan, Sheng Hai-Hui, Jin Lin, Shen Ya-Yun, Hua Qi, Lu Lin, Yu Jin-De, Huang Wei
Abstract excerpt
AIM: To discover single nucleotide polymorphisms (SNPs) in the promoter region of angiotensin II type 1 receptor (AT1) gene and evaluate their associations with the occurrence of essential hypertension (EH) and coronary heart disease (CHD) in Chinese Han population. METHODS: SNPs detection was performed by PCR-sequencing. The genotype was determined by the same method in a total number of 473 unrelated patients...
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