CYP7A1 genotypes and haplotypes associated with hypertension in an obese Han Chinese population.

doi:10.1038/hr.2011.18

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Article

CYP7A1 genotypes and haplotypes associated with hypertension in an obese Han Chinese population.

Hypertension research : official journal of the Japanese Society of Hypertension - 1 Jun 2011

Fu Lingyu, Zhao Yanyan, Wu Xiaomei, Liu Hong, Shi Jingpu, Lu Jingyu, Zhou Bo

Abstract excerpt

This study investigated the association between single-nucleotide polymorphisms (SNPs; rs3808607 and rs1125226) within the CYP7A1 promoter and hypertension susceptibility in a Han Chinese population. From 2003 through 2006, a population-based case-control study was performed in a cohort of 1187 randomly selected Han Chinese subjects. A sib-pair study for a transmission disequilibrium test analysis was carried out...

Topics

Adult
Case-Control Studies
China
Cholesterol 7-alpha-Hydroxylase
Female
Genotype
Haplotypes
Humans
Hypertension
Male
Middle Aged
Obesity
Polymorphism, Single Nucleotide
Promoter Regions, Genetic

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Open in PubMed

Identifiers

PMID: 21346769
DOI: 10.1038/hr.2011.18

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