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FUS‐Immunoreactive Intranuclear Inclusions in Neurodegenerative Disease

21 Sept 2009

Abstract excerpt

Neuronal intranuclear inclusions (NIIs) are a histopathological hallmark of several neurodegenerative disorders. However, the role played by NIIs in neurodegenerative pathogenesis remains enigmatic. Defining their molecular composition represents an important step in understanding the pathophysiology of these disorders. Recently, a nuclear protein, "fused-in-sarcoma" (FUS) was identified as the pathological...

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PMID: 19832837
DOI: 10.1111/j.1750-3639.2009.00337.x

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FUS‐Immunoreactive Intranuclear Inclusions in Neurodegenerative DiseasePMID 19832837Read ↗

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