Article
Characterization of Leishmania donovani variant clones using anti-lipophosphoglycan monoclonal antibodies.
Glycobiology - 1 Sept 1990
McNeely T B, Tolson D L, Pearson T W, Turco S J
Abstract excerpt
Monoclonal antibodies directed against the lipophosphoglycan of Leishmania donovani were used to characterize two glycosylation variants of the parasite. One of the variants was found to be totally deficient in the synthesis and expression of lipophosphoglycan. The other variant synthesized lower...
Topics
- Animals
- Antibodies, Monoclonal
- Autoradiography
- Carbon Radioisotopes
- Chromatography, Gas
- Chromatography, Gel
- Concanavalin A
- Electrophoresis, Polyacrylamide Gel
- Enzyme-Linked Immunosorbent Assay
- Galactose
- Genetic Variation
- Glycoproteins
- Glycosphingolipids
- Leishmania donovani
- Methylnitronitrosoguanidine
- Molecular Weight
- Mutagenesis
- Ricin