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Article

Association between polymorphism of tumor necrosis factor-alpha promoter and response to lamivudine treatment in patients with chronic hepatitis B.

Digestive diseases and sciences - 1 Jul 2010

Park Yong Kwang, Lee Jung Min, Kim Do Young, Chang Hye Young, Kim Ja Kyung, Lee Chun Kyon, Park Jun Yong, Ahn Sang Hoon, Lee Kwan Sik, Han Kwang Hyub

Abstract excerpt

BACKGROUND: TNF-alpha promoter polymorphism is known to play an important role in the immunopathogenesis of infection of hepatitis B virus. AIMS: We investigated whether polymorphisms of TNF-alpha promoter at position -308 or -238 had associations with the response to lamivudine treatment. METHODS: A total of 89 healthy subjects (control group) and 225 patients with chronic hepatitis B treated with lamivudine...

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Source

Identifiers

PMID: 19830555
DOI: 10.1007/s10620-009-0983-1

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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