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Article

Augmented stress-induced alcohol drinking and withdrawal in mice lacking functional natriuretic peptide-A receptors.

Alcohol and alcoholism (Oxford, Oxfordshire) - 1 Jan 2000

Mutschler Jochen, Bilbao Ainhoa, von der Goltz Christoph, Demiralay Cueneyt, Jahn Holger, Wiedemann Klaus, Spanagel Rainer, Kiefer Falk

Abstract excerpt

AIMS: Preclinical and clinical data suggest an involvement of atrial natriuretic peptides (ANP) in alcohol-associated psychopathology. We now present first data on alcohol drinking behaviour in mice lacking a functional natriuretic peptide-A (NPR-A) receptor. METHODS: NPR-A(-/-) and wild-type mice were given a free choice between water and increasing concentrations of alcohol (2-16%). A forced swim stress was...

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Identifiers

PMID: 19828462
DOI: 10.1093/alcalc/agp065

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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