Article
Genetic association studies in drug-induced liver injury.
Seminars in liver disease - 1 Nov 2009
Daly Ann K, Day Chris P
Abstract excerpt
Genetic studies on drug-induced liver injury (DILI) have proved challenging, both because of their rarity and their difficulty in replicating observed effects. However, significant progress has now been achieved by both candidate-gene and genome-wide association studies. These two approaches are considered in detail, together with examples of DILI due to specific drugs where consistent associations have been...
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