Article
Methionine synthase A2756G polymorphism and cancer risk: a meta-analysis.
European journal of human genetics : EJHG - 1 Mar 2010
Yu Ke, Zhang Jing, Zhang Jiyuan, Dou Chao, Gu Shaohua, Xie Yi, Mao Yumin, Ji Chaoneng
Abstract excerpt
Polymorphisms in methionine synthase (MTR) gene may be involved in carcinogenesis by affecting DNA methylation. However, association studies on MTR A2756G polymorphism in cancers have reported conflicting results. Therefore we performed a meta-analysis to better assess the associations. A total of 24 896 cancer patients and 33 862 controls from 52 articles for MTR A2756G were investigated. Overall, individuals...
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