A comprehensive resequence analysis of the KLK15-KLK3-KLK2 locus on chromosome 19q13.33.

doi:10.1007/s00439-009-0751-5

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

A comprehensive resequence analysis of the KLK15-KLK3-KLK2 locus on chromosome 19q13.33.

Human genetics - 1 Jan 2010

Parikh Hemang, Deng Zuoming, Yeager Meredith, Boland Joseph, Matthews Casey, Jia Jinping, Collins Irene, White Ariel, Burdett Laura, Hutchinson Amy, Qi Liqun, Bacior Jennifer A, Lonsberry Victor, Rodesch Matthew J, Jeddeloh Jeffrey A, Albert Thomas J, Halvensleben Heather A, Harkins Timothy T, Ahn Jiyoung, Berndt Sonja I, Chatterjee Nilanjan, Hoover Robert, Thomas Gilles, Hunter David J, Hayes Richard B, Chanock Stephen J, Amundadottir Laufey

Abstract excerpt

Single nucleotide polymorphisms (SNPs) in the KLK3 gene on chromosome 19q13.33 are associated with serum prostate-specific antigen (PSA) levels. Recent genome wide association studies of prostate cancer have yielded conflicting results for association of the same SNPs with prostate cancer risk. Since the KLK3 gene encodes the PSA protein that forms the basis for a widely used screening test for prostate cancer,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosomes, Human, Pair 19

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Haplotypes

Share to INDEL Mutation

Share to Kallikreins

Share to Linkage Disequilibrium

Share to Prostate-Specific Antigen

Share to Prostatic Neoplasms

Share to White People

Source

Open in PubMed Open full text

Identifiers

PMID: 19823874
DOI: 10.1007/s00439-009-0751-5
PMCID: PMC2793378

Genes

KLK3
MAF
KLK15
KLK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A comprehensive resequence analysis of the KLK15-KLK3-KLK2 locus on chromosome 19q13.33.PMID 19823874Read ↗

Fine mapping the KLK3 locus on chromosome 19q13.33 associated with prostate cancer susceptibility and PSA levels.Semantic proximity Read ↗

Identification of a novel prostate cancer susceptibility variant in the KLK3 gene transcript.Semantic proximity Read ↗

Tagging SNPs in the kallikrein genes 3 and 2 on 19q13 and their associations with prostate cancer in men of European origin.Semantic proximity Read ↗

Genetic polymorphisms in the human tissue kallikrein (KLK) locus and their implication in various malignant and non-malignant diseases.Semantic proximity Read ↗

Association of KLK3 (PSA) genetic variants with prostate cancer risk and PSA levels.Semantic proximity Read ↗

Multiple newly identified loci associated with prostate cancer susceptibility.Semantic proximity Read ↗

Biochemical activity induced by a germline variation in KLK3 (PSA) associates with cellular function and clinical outcome in prostate cancerSemantic proximity Read ↗

A PSA SNP associates with cellular function and clinical outcome in men with prostate cancer.Semantic proximity Read ↗

Association between three genetic variants in kallikrein 3 and prostate cancer riskSemantic proximity Read ↗

Comprehensive resequence analysis of a 123-kb region of chromosome 11q13 associated with prostate cancer.Semantic proximity Read ↗

Blood biomarker levels to aid discovery of cancer-related single-nucleotide polymorphisms: kallikreins and prostate cancer.Semantic proximity Read ↗

Common variation in Kallikrein genes KLK5, KLK6, KLK12, and KLK13 and risk of prostate cancer and tumor aggressiveness.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.