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Article

Common variation in Kallikrein genes KLK5, KLK6, KLK12, and KLK13 and risk of prostate cancer and tumor aggressiveness.

Urologic oncology - 1 Jul 2013

Lose Felicity, Batra Jyotsna, O'Mara Tracy, Fahey Paul, Marquart Louise, Eeles Ros A, Easton Douglas F, Al Olama Ali Amin, Kote-Jarai Zsofia, Guy Michelle, Muir Kenneth, Lophatananon Artitaya, Rahman Aneela A, Neal David E, Hamdy Freddie C, Donovan Jenny L, Chambers Suzanne, Gardiner Robert A, Aitken Joanne F, Yaxley John, Alexander Kimberly, Clements Judith A, Spurdle Amanda B, Kedda Mary-Anne

Abstract excerpt

The human tissue Kallikrein family consists of 15 genes with the majority shown to be differentially expressed in cancers and/or indicators of cancer prognosis. We sought to elucidate the role of common genetic variation in four of the Kallikrein genes, KLK5, KLK6, KLK12, and KLK13, in prostate c...

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Identifiers

PMID: 21741862
DOI: 10.1016/j.urolonc.2011.05.011

Genes

KLK12
KLK13
KLK5
KLK6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21741862-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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