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Article

Sch9 partially mediates TORC1 signaling to control ribosomal RNA synthesis.

Cell cycle (Georgetown, Tex.) - 15 Dec 2009

Wei Yuehua, Zheng X F Steven

Abstract excerpt

TORC1 is a central regulator of ribosomal RNA synthesis. Here we report that Sch9 partially mediates TORC1 signaling to regulate Pol I- and Pol III-dependent transcription. Mechanistically, Sch9 is involved in hyperphosphorylation and cytoplasmic localization of Maf1, and for optimal synthesis of...

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Share to Transcriptional Activation
Share to Gene Expression Regulation, Fungal
Share to Intracellular Signaling Peptides and Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Macromolecular Substances

Share to Phosphatidylinositol 3-Kinases

Share to RNA Polymerase I

Share to RNA, Ribosomal

Share to RNA, Transfer

Source

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Identifiers

PMID: 19823048
DOI: 10.4161/cc.8.24.10170
PMCID: PMC3023923

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19823048-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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