Article
Tor1 and CK2 kinases control a switch between alternative ribosome biogenesis pathways in a growth-dependent manner.
PLoS biology - 1 Mar 2017
Kos-Braun Isabelle C, Jung Ilona, Koš Martin
Abstract excerpt
Ribosome biogenesis is a major energy-consuming process in the cell that has to be rapidly down-regulated in response to stress or nutrient depletion. The target of rapamycin 1 (Tor1) pathway regulates synthesis of ribosomal RNA (rRNA) at the level of transcription initiation. It remains unclear whether ribosome biogenesis is also controlled directly at the posttranscriptional level. We show that Tor1 and casein...
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