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Article

CyclinD1 and interleukin-1 receptor antagonist polymorphisms are associated with prognosis in neoadjuvant-treated gastric carcinoma.

European journal of cancer (Oxford, England : 1990) - 1 Dec 2009

Stocker Gertraud, Ott Katja, Henningsen Nils, Becker Karen, Hapfelmeier Alexander, Lordick Florian, Hois Stefan, Plaschke Susanne, Höfler Heinz, Keller Gisela

Abstract excerpt

PURPOSE: We evaluated DNA polymorphisms in genes related to DNA repair, cell-cycle control and tumour microenvironment to determine possible associations with response and survival in neoadjuvant-treated gastric cancer patients. PATIENTS AND METHODS: One hundred and seventy eight patients who received platinum/5FU-based chemotherapy were genotyped for 10 polymorphisms in nine genes (ERCC1: Asn118Asn, C > T;...

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Source

Identifiers

PMID: 19822419
DOI: 10.1016/j.ejca.2009.09.021

Genes

ERCC1
TNF

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