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Article

Prognostic role of microRNA polymorphisms in advanced gastric cancer: a translational study of the Arbeitsgemeinschaft Internistische Onkologie (AIO).

Annals of oncology : official journal of the European Society for Medical Oncology - 1 Oct 2013

Stenholm L, Stoehlmacher-Williams J, Al-Batran S E, Heussen N, Akin S, Pauligk C, Lehmann S, Senff T, Hofheinz R D, Ehninger G, Kramer M, Goekkurt E

Abstract excerpt

BACKGROUND: To determine the prognostic role of selected microRNA (miRNA) polymorphisms in advanced gastric cancer (AGC). PATIENTS AND METHODS: Six hundred and seventy-four AGC patients received 5-fluorouracil (F), leucovorin (L), oxaliplatin (O) or FL + cisplatin (P) or additional docetaxel (T) to FLO (FLOT) within four clinical trials. Polymorphisms of mir-26a1 (rs7372209), mir-27a (rs895819), mir-100...

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PMID: 23975664
DOI: 10.1093/annonc/mdt330

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