Article
The prognostic value of four interleukin-1 gene polymorphisms in Caucasian women with breast cancer: a multicenter study.
BMC cancer - 6 Mar 2009
Grimm Christoph, Kantelhardt Eva, Heinze Georg, Polterauer Stephan, Zeillinger Robert, Kölbl Heinz, Reinthaller Alexander, Hefler Lukas
Abstract excerpt
BACKGROUND: The proinflammatory cytokine interleukin-1 (IL-1) is known to play an important role in the carcinogenesis of breast cancer. Although IL-1 gene polymorphisms were reported to be associated with increased risk of breast cancer, their influence on survival of Caucasian breast cancer patients remains to be shown. METHODS: We studied the influence of four common gene polymorphisms (IL1A -889C/T, IL1B...
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