Article
Induction of human TCR gamma delta + and TCR gamma delta-CD2+CD3- double negative lymphocytes by bacterial stimulation.
International immunology - 1 Jan 1990
Abo T, Sugawara S, Seki S, Fujii M, Rikiishi H, Takeda K, Kumagai K
Abstract excerpt
When human blood mononuclear cells (MNC) were incubated with heat-killed bacteria, proliferation of MNC was observed 5 days after stimulation, showing a peak on day 7. Interestingly, the bioassay of the culture supernatant and Northern blot analysis of mRNA demonstrated that no IL-2 production wa...
Topics
- Adult
- Antigens, Differentiation, T-Lymphocyte
- Bacteria
- CD2 Antigens
- CD3 Complex
- Cytotoxicity, Immunologic
- Humans
- In Vitro Techniques
- Infant, Newborn
- Interleukin-2
- Kinetics
- Lymphocyte Activation
- Phenotype
- Receptors, Antigen, T-Cell
- Receptors, Antigen, T-Cell, gamma-delta
- Receptors, Immunologic
- T-Lymphocytes
- Tuberculin