Article
Protective effect of interferon beta on human T cell leukaemia virus type I infection of CD4+ T cells isolated from human cord blood.
Cancer immunology, immunotherapy : CII - 1 Jul 1993
Macchi B, Faraoni I, Mastino A, D'Onofrio C, Romeo G, Bonmassar E
Abstract excerpt
The present study shows the effect of human interferon beta (IFN beta) on the susceptibility of highly purified cord blood CD4+ T cells to infection with the human T cell leukaemia virus type I (HTLV-I). Unfractionated cord blood mononuclear cells (CBMC), or a separated CD4+ T cell subpopulation...
Topics
- 2',5'-Oligoadenylate Synthetase
- CD4-Positive T-Lymphocytes
- Cytotoxicity, Immunologic
- Enzyme Induction
- Fetal Blood
- HTLV-I Infections
- Human T-lymphotropic virus 1
- Humans
- In Vitro Techniques
- Interferon-beta
- Phenotype
- Transcription, Genetic
- Viral Core Proteins