Article
Protective effect of interferon beta on human T cell leukaemia virus type I infection of CD4+ T cells isolated from human cord blood.
Cancer immunology, immunotherapy : CII - 1 Jul 1993
Macchi B, Faraoni I, Mastino A, D'Onofrio C, Romeo G, Bonmassar E
Abstract excerpt
The present study shows the effect of human interferon beta (IFN beta) on the susceptibility of highly purified cord blood CD4+ T cells to infection with the human T cell leukaemia virus type I (HTLV-I). Unfractionated cord blood mononuclear cells (CBMC), or a separated CD4+ T cell subpopulation (CBCD4) were exposed to HTLV-I by cocultivation with a chronically infected virus-donor cell line. The results show...
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