Article
Cytoplasmic membrane-associated protein (CAP) isolated from Streptococcus pyogenes: as a new bacterial superantigen.
Microbiology and immunology - 1 Jan 1994
Sato H, Itoh T, Rikiishi H, Kumagai K
Abstract excerpt
A protein isolated from the cytoplasmic membranes of Streptococcus pyogenes (cytoplasmic membrane-associated protein, CAP) stimulated human T cells in vitro to induce their mitogenic response. This CAP-induced T cell proliferation required the presence of nylon-adherent accessory cells (AC) of ei...
Topics
- Antigen-Presenting Cells
- Bacterial Proteins
- Cell Membrane
- Cytoplasm
- Histocompatibility Antigens Class II
- Humans
- In Vitro Techniques
- Lymphocyte Activation
- Membrane Proteins
- Phenotype
- Protein Binding
- Receptors, Antigen, T-Cell, alpha-beta
- Streptococcus pyogenes
- Superantigens
- T-Lymphocytes