Article
Association between T102C polymorphism of serotonin 2A receptor gene and urinary incontinence in older women.
Journal of investigative medicine : the official publication of the American Federation for Clinical Research - 1 Jan 2010
Noronha Jorge Antônio Pastro, Schwanke Carla Helena Augustin, Machado Denise Cantarelli, Braga Rafael, Lubianca Jeremia Mistrello, Sesti Fabiane Lorenzoni, de Toledo Aloysio Floriano, da Cruz Ivana Beatrice Mânica
Abstract excerpt
BACKGROUND: The bladder's regulatory function is influenced by central serotonergic modulation. T102C polymorphism of the serotonin 2A (5-HT(2A)) receptor gene is associated with urinary incontinence (UI) that has been reported by older community dwellers. We analyzed the association between 5-HT(2A) receptor gene polymorphism and urodynamic tests for UI in older women. METHODS: A case-control study was performed...
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