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Article

Association study of the 5-HT(2A) receptor gene polymorphism, T102C and essential hypertension.

Journal of human hypertension - 1 May 2001

Liolitsa D, Powell J F, Prince M, Lovestone S

Abstract excerpt

BACKGROUND: Serotonin dysfunction has been implicated in hypertension due to its ability to induce vasoconstriction via stimulation of 5-HT(2) receptors and due to the antihypertensive effect of ketanserin, an antagonist at the 5-HT(2A) receptor subtype, expressed both on arteries and the brain. The silent T102C polymorphism in the 5-HT(2A) gene is in absolute linkage disequilibrium with a polymorphism in the...

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Identifiers

PMID: 11378836
DOI: 10.1038/sj.jhh.1001177

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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