Article
Association analysis of 5-HTTLPR variants, 5-HT2a receptor gene 102T/C polymorphism and migraine.
Journal of neurogenetics - 1 Jan 2000
Juhasz Gabriella, Zsombok Terezia, Laszik Andras, Gonda Xenia, Sotonyi Peter, Faludi Gabor, Bagdy Gyorgy
Abstract excerpt
It is well known that migraine has a strong genetic component, although the type and number of genes involved is not yet clear. There is evidence to suggest that serotonin-related genes participate in the pathogenesis of migraine. Previous studies have shown that gender differences influence the serotonergic neurotransmission and, in addition, the migraine prevalence is higher in females than males. Therefore, we...
Topics
- Adult
- Carrier Proteins
- Case-Control Studies
- Chi-Square Distribution
- Female
- Genetic Predisposition to Disease
- Humans
- Logistic Models
- Membrane Glycoproteins
- Membrane Transport Proteins
- Migraine Disorders
- Migraine with Aura
- Migraine without Aura