Article
The -174 IL-6 GG genotype is associated with a reduced risk of type 2 diabetes mellitus in a family sample from the National Heart, Lung and Blood Institute's Framingham Heart Study.
Diabetologia - 1 Aug 2005
Herbert A, Liu C, Karamohamed S, Schiller J, Liu J, Yang Q, Wilson P W F, Cupples L A, Meigs J B
Abstract excerpt
AIMS/HYPOTHESIS: We evaluated the -174 IL-6 gene polymorphism as a risk factor for type 2 diabetes mellitus in a family-based analysis. METHODS: We tested for associations between the -174 IL-6 G/C promoter polymorphism and fasting plasma glucose (FPG) and type 2 diabetes in a sample of 1,428 individuals from the largest 182 families in the National Heart, Lung and Blood Institute's Framingham Heart Study...
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