Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polyamine-promoted autoactivation of plasma hyaluronan-binding protein.

Journal of thrombosis and haemostasis : JTH - 1 Mar 2010

Yamamichi S, Nishitani M, Nishimura N, Matsushita Y, Hasumi K

Abstract excerpt

BACKGROUND: Plasma hyaluronan-binding protein (PHBP), a protease implicated in extracellular proteolysis, consists of multiple domains: an N-terminal region (NTR), three epidermal growth factor (EGF)-like domains, a kringle domain, and a protease domain. PHBP circulates as a single-chain proenzyme (pro-PHBP), which is converted to an active, two-chain form through autoproteolysis. OBJECTIVE: To understand the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Allosteric Regulation
Share to Blood Coagulation
Share to Melanoma, Experimental

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Polyamines

Share to Protein Interaction Mapping

Share to Putrescine

Share to Spermidine

Share to Spermine

Source

Identifiers

PMID: 19817990
DOI: 10.1111/j.1538-7836.2009.03641.x

Genes

EGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polyamine-promoted autoactivation of plasma hyaluronan-binding protein.PMID 19817990Read ↗

Purification, Cloning, and Expression of Human Plasma HyaluronidaseSemantic proximity Read ↗

Hyaluronic Acid Plays Differential Molecular Weight and Concentration Dependent Pathway Centric Changes to Human Lung Derived Microvascular Endothelial Cells in CultureSemantic proximity Read ↗

Hyaluronan, Transforming Growth Factor β, and Extra Domain A-Fibronectin: A Fibrotic TriadSemantic proximity Read ↗

Anti-angiogenic action of plasma hyaluronan binding protein in human umbilical vein endothelial cells.Semantic proximity Read ↗

Regulation of ornithine decarboxylase activity and polyamine transport by agmatine in rat pulmonary artery endothelial cells.Semantic proximity Read ↗

Multistep autoactivation of asparaginyl endopeptidase in vitro and in vivo.Semantic proximity Read ↗

Increased Prolylcarboxypeptidase Expression Can Serve as Biomarker of Senescence in CultureSemantic proximity Read ↗

Clusters of basic amino acids in midkine: roles in neurite-promoting activity and plasminogen activator-enhancing activity.Semantic proximity Read ↗

Glycosaminoglycans facilitate procathepsin B activation through disruption of propeptide-mature enzyme interactions.Semantic proximity Read ↗

Polyarginine and its analogues inhibit p53 mutant aggregation and cancer cell proliferation in vitro.Semantic proximity Read ↗

Activation of ERK and NF-κB during HARE-Mediated Heparin Uptake Require Only One of the Four Endocytic Motifs.Semantic proximity Read ↗

Designed human serum hyaluronidase 1 variant, HYAL1DeltaL, exhibits activity up to pH 5.9.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.