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Article

Anti-angiogenic action of plasma hyaluronan binding protein in human umbilical vein endothelial cells.

International journal of oncology - 1 Jul 2006

Jeon Ji Won, Song Hyun Seok, Moon Eun-Joung, Park Shi-Young, Son Myung Jin, Jung Seung Youn, Kim Ji Tae, Nam Do-Hyun, Choi-Miura Nam-Ho, Kim Kyu-Won, Kim Yung-Jin

Abstract excerpt

The kringle domain is a triple loop structure present in angiostatin and endostatin. The disulfide bond-linked kringle architectures have been known to be essential for anti-angiogenic activity. Plasma hyaluronan binding protein (PHBP) is a novel serine protease which consists of three epidermal growth factor (EGF) domains, a kringle domain, and a serine protease domain. PHBP can be cleaved autocatalytically to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16773202

Genes

EGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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