Article
Smooth muscle cell phenotype modulation and contraction on native and cross-linked polyelectrolyte multilayers.
Biomacromolecules - 9 Nov 2009
Moussallem Maroun D, Olenych Scott G, Scott Shannon L, Keller Thomas C S, Schlenoff Joseph B
Abstract excerpt
Smooth muscle cells convert between a motile, proliferative "synthetic" phenotype and a sessile, "contractile" phenotype. The ability to manipulate the phenotype of aortic smooth muscle cells with thin biocompatible polyelectrolyte multilayers (PEMUs) with common surface chemical characteristics but varying stiffness was investigated. The stiffness of (PAH/PAA) PEMUs was varied by heating to form covalent amide...
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