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Article

Modular polymer design to regulate phenotype and oxidative response of human coronary artery cells for potential stent coating applications.

Acta biomaterialia - 1 Feb 2012

Crowder Spencer W, Gupta Mukesh K, Hofmeister Lucas H, Zachman Angela L, Sung Hak-Joon

Abstract excerpt

Polymer properties can be tailored by copolymerizing subunits with specific physico-chemical characteristics. Vascular stent materials require biocompatibility, mechanical strength, and prevention of restenosis. Here we copolymerized poly(ε-caprolactone) (PCL), poly(ethylene glycol) (PEG), and carboxyl-PCL (cPCL) at varying molar ratios and characterized the resulting material properties. We then performed a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22019760
DOI: 10.1016/j.actbio.2011.10.003
PMCID: PMC3253951

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