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Article

Molecular cloning and characterisation of the RESA gene, a marker of genetic diversity of Plasmodium falciparum.

Molecular biology reports - 1 Jul 2010

Moyano Eva M, González Luis Miguel, Cuevas Laureano, Perez-Pastrana Esperanza, Santa-Maria Ysmael, Benito Agustín

Abstract excerpt

To identity immunodiagnostic antigen genes, a Plasmodium falciparum (Dd2 clone) expression library was screened using human immune sera. The ring-infected erythrocyte surface antigen (RESA) was isolated: this antigen of the resistant clone presents repeat tandem sequences like the 3D7 clone, albeit in different numbers. RESA has been studied as a marker of genetic diversity, with different sizes being observed in...

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Identifiers

PMID: 19816792
DOI: 10.1007/s11033-009-9849-z
PMCID: PMC2900597

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