Article
Comparative transcriptomal analysis of isogenic Plasmodium falciparum clones of distinct antigenic and adhesive phenotypes.
Molecular and biochemical parasitology - 1 Feb 2007
Mok Bobo W, Ribacke Ulf, Winter Gerhard, Yip Ben H, Tan Chuen-Seng, Fernandez Victor, Chen Qijun, Nilsson Peter, Wahlgren Mats
Abstract excerpt
Antigenic variation is a survival mechanism developed by the malaria parasite Plasmodium falciparum in order to allow for the establishment of a chronic infection. Here we have studied clonal differences in the transcriptomes of two isogenic P. falciparum clones (3D7S8.4 and 3D7AH1S2) of distinct adhesive and antigenic phenotypes employing a P. falciparum 70-mer oligonucleotide microarray. Fifteen transcripts...
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