Article
The S-antigen of Plasmodium falciparum: repertoire and origin of diversity.
Molecular and biochemical parasitology - 1 Oct 1993
Bickle Q, Anders R F, Day K, Coppel R L
Abstract excerpt
S-antigens are heat-stable, highly polymorphic proteins released by Plasmodium falciparum at the time of schizont rupture. Previously determined S-antigen sequences allowed the proposal of a general gene structure consisting of 5 sequence blocks. The sequence of the central block of tandem repeats provides a useful means of distinguishing the S-antigen allele and also its serotype, whereas the amino and carboxy...
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