Article
A role for the Plasmodium falciparum RESA protein in resistance against heat shock demonstrated using gene disruption.
Molecular microbiology - 1 May 2005
Silva Monica Diez, Cooke Brian M, Guillotte Micheline, Buckingham Donna W, Sauzet Jean-Pierre, Le Scanf Cecile, Contamin Hugues, David Peter, Mercereau-Puijalon Odile, Bonnefoy Serge
Abstract excerpt
During erythrocyte invasion, the Plasmodium falciparum Ring-infected erythrocyte surface antigen (RESA) establishes specific interactions with spectrin. Based on analysis of strains with a large chromosome 1 deletion, RESA has been assigned several functions, none of which is firmly established. Analysis of parasites with a disrupted resa1 gene and isogenic parental or resa3-disrupted controls confirmed the...
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