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Article

Complement-Dependent Inflammation and Injury in a Murine Model of Brain Dead Donor Hearts

8 Oct 2009

Abstract excerpt

RATIONALE: Donor brain death (BD) is an unavoidable occurrence in heart transplantation and results in profound physiological derangements that render the heart more susceptible to ischemia/reperfusion injury in the recipient and likely has negative long-term consequences to allograft survival. OBJECTIVE: We developed a novel mouse model of BD and investigated the role of complement in BD-induced myocardial...

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Identifiers

PMID: 19815824
DOI: 10.1161/circresaha.109.194977

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