Article
Variation in the human soluble epoxide hydrolase gene and risk of restenosis after percutaneous coronary intervention.
BMC cardiovascular disorders - 8 Oct 2009
Kullmann Silke, Binner Priska, Rackebrandt Kirsten, Huge Andreas, Haltern Georg, Lankisch Mark, Füth Reiner, von Hodenberg Eberhard, Bestehorn Hans-Peter, Scheffold Thomas
Abstract excerpt
BACKGROUND: Restenosis represents the major limiting factor for the long-term efficacy of percutaneous coronary intervention (PCI). Several genetic factors involved in the regulation of the vascular system have been described to play a role in the pathogenesis of restenosis. We investigated whether the EPHX2 K55R polymorphism, previously linked to significantly higher risk for coronary heart disease (CHD), was...
Topics
- Adult
- Aged
- Angioplasty, Balloon, Coronary
- Calcium Channel Blockers
- Case-Control Studies
- Coronary Angiography
- Coronary Disease
- Coronary Restenosis
- Epoxide Hydrolases
- Europe
- Female
- Gene Frequency
- Genetic Predisposition to Disease