Article
Matrix metalloproteinases 2 and 3 gene polymorphisms and the risk of target vessel revascularization after percutaneous coronary intervention: Is there still room for determining genetic variation of MMPs for assessment of an increased risk of restenosis?
Disease markers - 1 Jan 2010
Verschuren J J W, Sampietro M L, Pons D, Trompet S, Ewing M M, Quax P H A, de Knijff P, Zwinderman A H, de Winter R J, Tio R A, de Maat M P, Doevendans P A F M, Jukema J W
Abstract excerpt
OBJECTIVE: Mixed results have been reported of matrix metalloproteinases (MMP) and their association with restenosis after percutaneous coronary intervention (PCI). The current study examines whether multiple single nucleotide polymorphisms (SNPs), covering the full genomic region of MMP2 and MMP3, were associated with restenosis in the GENDER study population. METHODS AND RESULTS: The GENetic DEterminants of...
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