Article
Association of soluble endothelial protein C receptor plasma levels and PROCR rs867186 with cardiovascular risk factors and cardiovascular events in coronary artery disease patients: the Athero Gene study.
BMC medical genetics - 8 Nov 2012
Kallel Choumous, Cohen William, Saut Noémie, Blankenberg Stefan, Schnabel Renate, Rupprecht Hans J, Bickel Christoph, Munzel Thomas, Tregouet David-Alexandre, Morange Pierre-Emmanuel
Abstract excerpt
BACKGROUND: Blood coagulation is an essential determinant of coronary artery disease (CAD). Soluble Endothelial Protein C Receptor (sEPCR) may be a biomarker of a hypercoagulable state. We prospectively investigated the relationship between plasma sEPCR levels and the risk of cardiovascular events (CVE). METHODS: We measured baseline sEPCR levels in 1673 individuals with CAD (521 with acute coronary syndrome...
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