Article
Chronic family stress interacts with 5-HTTLPR to predict prospective depressive symptoms among youth.
Depression and anxiety - 21 Dec 2011
Jenness Jessica L, Hankin Benjamin L, Abela John R Z, Young Jami F, Smolen Andrew
Abstract excerpt
BACKGROUND: Previous research, predominantly with adults, has shown that the serotonin transporter gene (5-HTTLPR) interacts with stress (G × E) to predict depressive symptoms; however, few G × E studies have been conducted with youth using rigorous methods, particularly a prospective design and contextual interview to assess stress. This study examined the interaction between 5-HTTLPR and stress, both chronic...
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