Article
Genetic variation in N-acetyltransferases 1 and 2, cigarette smoking, and risk of non-Hodgkin lymphoma.
Cancer causes & control : CCC - 1 Jan 2010
Kilfoy Briseis A, Zheng Tongzhang, Lan Qing, Han Xuesong, Holford Theodore, Hein David W, Qin Qin, Leaderer Brian, Morton Lindsay M, Yeager Meredith, Boyle Peter, Zhao Ping, Chanock Stephen, Rothman Nathaniel, Zhang Yawei
Abstract excerpt
Cigarette smoke contains many carcinogens that are metabolically activated through xenobiotic metabolism by phase I and II enzymes, including N-acetyltransferases 1 and 2 (NAT1 and NAT2). We investigated non-Hodgkin lymphoma risk in general and by subtype in relation to NAT1 and NAT2 genotypes and cigarette smoking in a population-based case-control study in Connecticut. Of the 535 controls, 53.1% reported ever...
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