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Article

AML1/RUNX1 mutations in 470 adult patients with de novo acute myeloid leukemia: prognostic implication and interaction with other gene alterations.

Blood - 17 Dec 2009

Tang Jih-Luh, Hou Hsin-An, Chen Chien-Yuan, Liu Chieh-Yu, Chou Wen-Chien, Tseng Mei-Hsuan, Huang Chi-Fei, Lee Fen-Yu, Liu Ming-Chih, Yao Ming, Huang Shang-Yi, Ko Bor-Sheng, Hsu Szu-Chun, Wu Shang-Ju, Tsay Woei, Chen Yao-Chang, Lin Liang-In, Tien Hwei-Fang

Abstract excerpt

Somatic mutation of the AML1/RUNX1(RUNX1) gene is seen in acute myeloid leukemia (AML) M0 subtype and in AML transformed from myelodysplastic syndrome, but the impact of this gene mutation on survival in AML patients remains unclear. In this study, we sought to determine the clinical implications...

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Source

Identifiers

PMID: 19808697
DOI: 10.1182/blood-2009-05-223784

Genes

RUNX1
NPM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19808697-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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AML1/RUNX1 mutations in 470 adult patients with de novo acute myeloid leukemia: prognostic implication and interaction with other gene alterations.PMID 19808697Read ↗

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