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Article

Visualizing the von Willebrand factor/glycoprotein Ib-IX axis with a platelet-type von Willebrand disease mutation.

Blood - 24 Dec 2009

Guerrero Jose A, Kyei Mark, Russell Susan, Liu Junling, Gartner T Kent, Storrie Brian, Ware Jerry

Abstract excerpt

Platelet-type von Willebrand disease (PT-VWD) is a bleeding disorder of the platelet glycoprotein Ib-IX/von Willebrand factor (VWF) axis caused by mutations in the glycoprotein Ib-IX receptor that lead to an increased affinity with VWF. In this report, platelets from a mouse expressing a mutation associated with PT-VWD have been visualized using state-of-the art image collection and processing. Confocal analysis...

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Source

Open in PubMed Open full text

Identifiers

PMID: 19808696
DOI: 10.1182/blood-2009-03-210823
PMCID: PMC2798865

Genes

VWF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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