Article
Mouse models to study von Willebrand factor structure-function relationships in vivo.
Hamostaseologie - 1 Jan 2009
Denis C V, Marx I, Badirou I, Pendu R, Christophe O
Abstract excerpt
Von Willebrand factor (VWF) structure-function relationship has been studied only through in vitro approaches. The VWF-deficient mouse model has been extremely useful to examine the in vivo function of VWF but does not allow a more subtle analysis of the relative importance of its different domains. However, considering the large size of VWF and its capacity to interact with various ligands in order to support...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
