Article
N-Acetyl-D-Glucosamine Kinase Interacts with NudC and Lis1 in Dynein Motor Complex and Promotes Cell Migration.
International journal of molecular sciences - 24 Dec 2020
Islam Md Ariful, Choi Ho Jin, Dash Raju, Sharif Syeda Ridita, Oktaviani Diyah Fatimah, Seog Dae-Hyun, Moon Il Soo
Abstract excerpt
Recently, we showed that N-acetylglucosamine kinase (NAGK), an enzyme of amino sugar metabolism, interacts with dynein light chain roadblock type 1 (DYNLRB1) and promotes the functions of dynein motor. Here, we report that NAGK interacts with nuclear distribution protein C (NudC) and lissencephaly 1 (Lis1) in the dynein complex. Yeast two-hybrid assays, pull-down assays, immunocytochemistry, and proximity...
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