Article
Human apolipoprotein A-I gene promoter polymorphism: association with hyperalphalipoproteinemia.
Journal of lipid research - 1 Aug 1990
Pagani F, Sidoli A, Giudici G A, Barenghi L, Vergani C, Baralle F E
Abstract excerpt
An apolipoprotein A-I gene promoter polymorphism, due to an adenine (A) to guanine (G) transition 78 base pairs upstream from the transcription initiation site, was studied by amplification of the corresponding region of the apoA-I gene, DNA sequencing, and allele-specific oligonucleotide hybridization. The frequency of the polymorphism was studied on female and male individuals classified into three groups...
Topics
- Adult
- Alleles
- Apolipoprotein A-I
- Apolipoproteins A
- Base Sequence
- Female
- Genes
- Genotype
- Humans
- Hyperlipoproteinemias
- Lipoproteins, HDL
- Male
