Article
Genetic analysis of a polymorphism in the human apolipoprotein A-I gene promoter: effect on plasma HDL-cholesterol levels.
Journal of lipid research - 1 Jul 1994
Barre D E, Guerra R, Verstraete R, Wang Z, Grundy S M, Cohen J C
Abstract excerpt
Previous studies have indicated that a G to A substitution at position -76 in the gene encoding apolipoprotein A-I (apoA-I) confers increased plasma high density lipoprotein cholesterol (HDL-C). Increased HDL-C may be a direct consequence of the A allele, or may reflect the action of a locus in linkage disequilibrium with the A allele. To elucidate this question, we examined the effect of this polymorphism in a...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
