Genetic analysis of a polymorphism in the human apolipoprotein A-I gene promoter: effect on plasma HDL-cholesterol levels.

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Article

Genetic analysis of a polymorphism in the human apolipoprotein A-I gene promoter: effect on plasma HDL-cholesterol levels.

Journal of lipid research - 1 Jul 1994

Barre D E, Guerra R, Verstraete R, Wang Z, Grundy S M, Cohen J C

Abstract excerpt

Previous studies have indicated that a G to A substitution at position -76 in the gene encoding apolipoprotein A-I (apoA-I) confers increased plasma high density lipoprotein cholesterol (HDL-C). Increased HDL-C may be a direct consequence of the A allele, or may reflect the action of a locus in l...

Topics

Adenine
Adolescent
Adult
Aged
Aged, 80 and over
Alleles
Apolipoprotein A-I
Cholesterol, HDL
Female
Guanine
Homozygote
Humans
Male
Middle Aged
Polymorphism, Genetic
Promoter Regions, Genetic

Source

Open in PubMed

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PMID: 7964190

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7964190-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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