Article
A polymorphism in the human apolipoprotein AI promoter region: a study in hypertriglyceridaemic patients.
Human heredity - 1 Jan 2000
Needham E W, Mattu R K, Rees A, Stocks J, Galton D J
Abstract excerpt
We examined the impact of a G-->A mutation at position -75 of the apolipoprotein AI gene promoter in subjects with hypertriglyceridaemia from two racial groups, Caucasians (n = 52) and Japanese (n = 19) compared to their controls (n = 56 and n = 21 respectively). The mutation was genotyped by the polymerase chain reaction and subsequent digestion using HpaII, and BstNI. We found no significant differences in...
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